Purpose: To gather information that may be useful in helping a loved one who suffers from this condition.
Showing posts with label genetics. Show all posts
Showing posts with label genetics. Show all posts
24 September 2014
20 September 2013
Atopic syndrome
- "Atopic syndrome is a predisposition toward developing certain allergic hypersensitivity reactions. Atopy may have a hereditary component, although contact with the allergen must occur before the hypersensitivity reaction can develop."
- Many EE patients suffer from concurrent autoimmune and allergic disease.
- Patients with atopy usually develop what is referred to as the “allergic triad” of symptoms, i.e., eczema (atopic dermatitis), hay fever (allergic rhinitis), and allergy-induced asthma (allergic asthma).
- They also have a tendency to have food allergies, and other symptoms characterized by their hyperallergic state. For example, eosinophilic esophagitis is found associated with atopic allergies.
- Although atopy has various definitions, in general, it is defined by the presence of elevated levels of total and allergen-specific IgE in the serum, leading to positive skin-prick tests to common allergens.
- There is a strong genetic predisposition toward atopic allergies, especially on the maternal side.
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