23 September 2013

Various effects of different probiotic strains in allergic disorders

Various effects of different probiotic strains in allergic disorders: an update from laboratory and clinical data
-Ozdemir O., Department of Pediatics, Division of Allergy/Immunology, SEMA Research and Training Hospital, Istanbul, Turkey
Clin Exp Immunol. 2010 Jun;160(3):295-304. doi: 10.1111/j.1365-2249.2010.04109.x. Epub 2010 Mar 16.

Excerpts:
  • Enhanced presence of probiotic bacteria in the intestinal microbiota is found to correlate with protection against atopy. 
  • There is also very promising evidence to recommend the addition of probiotics to foods for the prevention and treatment of allergic diseases. 
  • Clinical improvement, especially in allergic rhinitis and immunoglobulin (Ig)E-sensitized (atopic) eczema, has been reported in most of the published studies.  
  • After weaning, the microflora of children begins to resemble that of adults, with
    increased Bacteroides, Veillonella and Fusobacterium.
  • In another study, Lctbs acidophilus and Bfdbm lactis treatments prevented OVA-induced allergic symptoms on the skin and gastrointestinal tract, e.g. eosinophilic infiltration.
Editor's notes:
  • The 'hygiene hypothesis' and its possible connection to increased levels of allergic disease in industrialized countries.
  • Development of infant immune system, its relation to environmental and dietary bacteria, and its maturation into the adult immune system.
  • Probiotics: definition and modes of operation.

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